Richard Harris http://kttz.org en First Embryonic Stem Cells Cloned From A Man's Skin http://kttz.org/post/first-embryonic-stem-cells-cloned-mans-skin Eighteen years ago, scientists in Scotland took the nuclear DNA from the cell of an adult sheep and put it into another sheep's egg cell that had been emptied of its own nucleus. The resulting egg was implanted in the womb of a third sheep, and the result was Dolly, the first clone of a mammal.<p>Dolly's birth set off a huge outpouring of ethical concern — along with hope that the same techniques, applied to human cells, could be used to treat myriad diseases.<p>But Dolly's birth also triggered years of frustration. Thu, 17 Apr 2014 18:14:00 +0000 Richard Harris 42766 at http://kttz.org First Embryonic Stem Cells Cloned From A Man's Skin Ebola Drug Could Be Ready For Human Testing Next Year http://kttz.org/post/ebola-drug-could-be-ready-human-testing-next-year The <a href="http://www.npr.org/blogs/health/2014/04/08/300509073/the-ebola-outbreak-three-weeks-in-dire-but-not-hopeless">Ebola outbreak</a> in West Africa is terrifying because there's no drug to treat this often fatal disease. But the disease is so rare, there's no incentive for big pharmaceutical companies to develop a treatment.<p>Even so, some small companies, given government incentives, are stepping into that breach. The result: More than half a dozen ideas are being pursued actively.<p>And these are boon days for drugs that can treat viruses. Fri, 11 Apr 2014 20:06:00 +0000 Richard Harris 42465 at http://kttz.org Ebola Drug Could Be Ready For Human Testing Next Year How Mouse Studies Lead Medical Research Down Dead Ends http://kttz.org/post/how-mouse-studies-lead-medical-research-down-dead-ends Most experimental drugs fail before they make it through all the tests required to figure out if they actually work and if they're safe. But some drugs get fairly far down that road, at the cost of hundreds of millions of dollars, based on poorly conducted studies at the outset.<p>Medical researchers reviewing this sorry state of affairs say the drug-development process needs serious improvement.<p>Consider drugs that are being developed to treat <a href="http://www.nlm.nih.gov/medlineplus/amyotrophiclateralsclerosis.html">ALS</a>, or Lou Gehrig's disease. Tue, 08 Apr 2014 07:44:00 +0000 Richard Harris 42198 at http://kttz.org How Mouse Studies Lead Medical Research Down Dead Ends Simple Blood Test To Spot Early Lung Cancer Getting Closer http://kttz.org/post/simple-blood-test-spot-early-lung-cancer-getting-closer One of these days, there could well be a simple blood test that can help diagnose and track cancers. We aren't there yet, but a burst of research in this area shows we are getting a lot closer.<p>In the latest of these studies, scientists have used blood samples to identify people with lung cancer.<p>At the Stanford School of Medicine, <a href="http://stemcell.stanford.edu/about/Laboratories/diehn/index.html">Dr. Maximilian Diehn</a> spends some of his time as a radiation oncologist treating patients with cancer, and some of his time delving into the world of DNA. Sun, 06 Apr 2014 17:22:00 +0000 Richard Harris 42132 at http://kttz.org Simple Blood Test To Spot Early Lung Cancer Getting Closer Custom Chromo: First Yeast Chromosome Built From Scratch http://kttz.org/post/custom-chromo-first-yeast-chromosome-built-scratch Using the labor of dozens of undergraduate students, scientists have built a customized yeast chromosome from scratch.<p>It's a milestone in the rapidly growing field of synthetic biology, where organisms can be tailored for industrial use. In this case, the near-term goal is to understand the genetics of yeast, and eventually the genetics of us.<p>This was quite an undertaking. Yeast have about 6,000 genes packed in 16 tidy bundles called chromosomes. Thu, 27 Mar 2014 21:05:00 +0000 Richard Harris 41598 at http://kttz.org Custom Chromo: First Yeast Chromosome Built From Scratch